14-3-3 zeta anticorps (pSer58) (AbBy Fluor® 594)

N° du produit ABIN2809283

Cet anticorps anti-14-3-3 zeta est un anticorps Lapin Polyclonal détectant 14-3-3 zeta dans WB et FACS. Adapté pour Humain.

Aperçu rapide pour 14-3-3 zeta anticorps (pSer58) (AbBy Fluor® 594) (ABIN2809283)

Antigène: 14-3-3 zeta (YWHAZ)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 zeta est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-14-3-3 zeta anticorps (AbBy Fluor® 594)

Épitope: pSer58

Specificité: This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR.

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR]

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur 14-3-3 zeta

Antigène: 14-3-3 zeta (YWHAZ)

Autre désignation: 14-3-3 Protein zeta/ delta

Sujet:

Synonyms: YWHAEphospho S58, YWHAZphospho S58, 14 3 3, 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta, 14-3-3 protein beta/alpha, KCIP 1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB, YWHAZ, GW128, HS1, KCIP-1, YWHAE, YWHAA, 1433Z_HUMAN, Full=14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1.

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

ID gène: 7534, 7529, 10971

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location